Tagged: DHT

Azelaic Acid Hair Loss treatment

In today’s world, hair loss is one of the major problems that people face on a day to day basis. Various factors like stress and hard water, contribute to the receding hairlines that are becoming more and more common. To prevent hair loss, a lot of people use various hair loss treatments. There are specific creams available in the market to reduce and prevent baldness. A lot of conditioners also guarantee prevention of hair loss. However, when the hair loss is related to enzyme secretion, something specific is required.

Revolutionary cause of hair loss discovered

One of the causes of hair loss can be an increased production of an enzyme called 5 alpha reductase, and this enzyme is excreted from the scalp through the adrenal glands. 5 alpha reductase breaks down Dihydrotestosterone from testosterone, which is also present in women, although in smaller quantities. It is this Dihydrotestosterone that results in baldness. When Dihydrotestosterone attaches itself to hair follicles, it destroys them, thereby inhibiting growth of hair. However, hair loss caused due to excessive production of 5 alpha reductase is reversible. It is obvious then, that to prevent hair loss, one needs to inhibit the production of 5 alpha reducaste, especially in the scalp. One of the compounds that help in the reduction of this enzyme is Azelaic Acid.

All about Azelaic acid

Because of Azelaic Acid, hair loss is not a major problem anymore. It is also known as 1,9 Nonanedioic Acid. Azelaic Acid, which is naturally occurring in some whole grains, is usually applied to the scalp. The Azelaic Acid that is applied prevents Dihydrotestosterone from binding to the hair follicles. This prevents hair loss and encourages re-growth. Thus, Azelaic acid becomes a necessary ingredient of various conditioners, shampoos and hair tonics which promise re growth of hair. Azelaic Acid works best with a particular concentration of Zinc Sulphate, and this combination is said to have a 100 percent prevention rate of Dihydrotestosterone attaching itself to the hair follicles.

Using Azelaic Acid hair loss can be conquered. The side effects of this include rashes and stinging among others. But statistically, a very less percentage of people show the symptoms of the side effects. However, products with Azelaic Acid might be harmful to small children. Therefore, the products which contain Azelaic Acid should not be used on children.

Hair loss – A thing of the past

With the discovery of Azelaic Acid as an inhibitor of 5 alpha reductase, hair loss does not remain anything to worry about anymore. If one does not want to use a lot of chemical products to reduce hair loss, then one can just increase the presence of whole grains in the diet. As Azelaic Acid is present in most of whole grains, hair fall reduction is guaranteed with an increase in the presence of whole grains in one’s diet.  Through Azelaic Acid for hair loss has been scientifically proven to have reduced considerably. Thus, it becomes a good option to consider if one is facing a crisis regarding hair loss.

Does dandruff cause hair loss?

Dandruff is among one of the major hair problems. Many people assume that dandruff is a normal condition, but they don’t know that it could result in hair loss. Dandruff is basically a scalp disorder wherein scalp flakes come out. These scalp flakes are nothing but dead skin cells. Infection by bacteria and fungus is responsible for dandruff that can lead to an itchy and dry scalp that is not only irritating, but if dandruff is not cured then it may result in serious hair loss. There are numerous reasons that may lead to dandruff.

Dandruff causes – Reasons galore

  • Mental stress
  • Lack of nutritious diet
  • Hereditary reasons
  • Not taking care of proper cleansing your scalp or using excessive anti dandruff shampoo
  • Frequent change in shampoo brands and conditioners
  • Hormonal imbalance
  • Prolonged illness
  • Excessive oil production on scalp
  • Seasonal conditions like dry winter air
  • Skin conditions like acne, eczema, etc that lead to the formation of dead skin on the scalp
  • Frequent use of hair styling products
  • Over exposure to the sun

All these reasons lead to the formation of dead skin cells. It is pointless to say that if proper remedy is not figured out, then dandruff can result in hair loss. Nevertheless, dandruff is neither a serious hair disorder, nor it is contagious; but it really causes lot of embarrassment and may create an inferiority complex.  Figuring out about inexpensive and effective remedies for curing dandruff is no rocket science as it can be treated by some simple and inexpensive home remedies. So when we are aware by now that dandruff may lead to hair fall, let’s have a glance on the best home remedies for treating dandruff.

Homemade remedies to cure dandruff problems

  • Messaging with almond oil, coconut oil really proves to be extremely helpful in dandruff treatment.
  • A nutritious diet containing protein, zinc, iron, vitamin C, vitamin E, and vitamin B12 is a sure shot way to get rid of irritating dandruff and to promote hair growth.
  • Drinking plenty of water promotes helps in the reduction of hair fall.
  • Rinsing hair properly after applying shampoo and conditioner is extremely important because at times, the leftovers lead to the formation of dandruff.
  • Detangling hair by using wide-comb can really make a big difference. Another most important point to remember is to pay utmost attention to the cleanliness of the combs, towel, hair accessories, etc.

Does dandruff cause hair loss? – The flip side

Well, there is another set of believers who believe that dandruff doesn’t lead to hair loss. However, dandruff may not be a direct and conspicuous reason of hair loss, but it certainly contributes in deteriorating the quality of hair. Both, excessive dry or excessive oily scalp causes dandruff. In case of oily scalp, yellow flakes are formed and in case of excessive dry scalp, white flakes are formed. If scalp itself would not be in a good condition, then hair strands will not be able to develop in a proper way. Dead cells would discourage the growth of new hair strands. For allowing hair to grow healthy, it is important to keep the scalp healthy and free from dead cells. To sum up, whether dandruff leads to hair loss or not, there is no doubt that by curing dandruff one can experience healthy hair.

Should You Use the Nizoral Hair Loss Shampoo?

In the event that you are faced with problems caused by hair loss or dandruff, you surely heard about Nizoral hair loss shampoos. This is basically a treatment that is based on ketaconazole that is included at a potency of 1 or 2 percent. The claim is that this shampoo is going to control dry scalp, which stands out as the main cause of having to deal with dandruff. In addition, if you are faced with a dry scalp you can end up with itchiness and skin inflammation.

Behind Nizoral formula

As already mentioned, the active ingredient that is used in the Nizoral hair loss and dandruff formula is ketoconazole. There is scientific evidence that shows the fact that this substance can actively control the levels of dihydrotestosterone we have. DHT stands out as the biggest cause of thinning areas and balding spots for both women and men. It will appear when faced with too much testosterone is combined with 5-Alpha Reductase. In the event that you do not get rid of scalp DHT you are going to end up with hair follicles that become dormant or inactive. All this basically means that, in theory, the use of Nizoral is going to guarantee that you take care of the main problem that is causing hair loss. The product has been designed in order to leave hair manageable while also eliminating dandruff, itchiness and dry scalp.

What kind of results can you expect?

Most people are going to hurry and they are going to expect immediate results from the Nizoral hair loss formula. You should not hurry but it is also great to notice that not too much time has to be expected. In around 2 to 4 weeks there is a very strong chance that you are going to notice improvements on the scalp skin condition. This basically shows you that the product will be working. We recommend that you properly massage the shampoo into the scalp so that every single follicle can be reached. The extra added benefits of doing this are brought in by being able to eliminate dirt, fungus, bacteria and different environmental toxins.

What is really interesting is the fact that there is no claim from the manufacturer that there are Nizoral hair loss benefits that will be guaranteed. The only real guarantee is that the product can actively fight dandruff. However, due to the fact that we are faced with the introduction of ketoconazole, this is definitely an advantage that is possible with most people.

In conclusion we need to say that in the event that you are suffering from hair loss, you should seriously consider giving Nizoral a try. You might even talk to your doctor. What is important is to understand the reason why your hair is falling. If Nizoral can help there is absolutely no reason why you should not try it. The only real problem is that it can be quite expensive if you buy it from a local pharmacy. It might be a much better solution to opt for Internet stores as the prices are cheaper.

Androgenetic Alopecia treatments, when the hormonal imbalances attacks

Androgenetic Alopecia is the common hair loss problem that can affect both male and female of all walks of life. It is basically more prevalent in men than with women. It is said that over 50% of men are affected by this particular problem in many parts of the world. Women basically get this problem when they are over 40 years.

androgenic_alopecia_treatmentsThe problem mainly affects women who are past menopause age. It is also estimated that over 75% of cases of women of over 65 years of age are affected by this particular problem of androgenetic alopecia. Looking at the racial statistics, the problem is more prevalent in white men, followed by Asians, African Americans and the prevalence rates are very low with the Latin world.

The problem of androgenetic alopecia as the name suggests is basically determined by genetics.

It is therefore necessary to note that and androgenetic alopecia treatments can only be seen to solve the issue of hair loss in some cases, while others it may be too difficult to prescribe a lasting solution.

Another thing that is important to note is that cases of androgenetic alopecia may also be idiopathic. That actually means that it may not be a detectable condition of the hormonal imbalance that may give rise to the problem of the hair loss. Blood tests may be conducted, but in such a case may not bring out any particular issue that may be perceived to be away from the ordinary.

We can therefore not in all cases get androgenetic alopecia treatments out of addressing the problem of hormonal imbalances. That is a case that may also be beyond the attention of a dermatologist.

What options do you have?

Androgenetic alopecia treatments that are in form of supplements are also available. These are more recommended for women as men may suffer from their side effects more.

Women’s androgenetic alopecia treatments are many. There are also some herbal treatments that are very much available in the market for particularly women. These are said to be similar to the estrogen which will basically shield a woman from the side effects of androgens.

There is an observation in the medical arena that many treatments are seen to have a lot of successes in women more than men. Some monoxidil solutions when used together with other therapies are said to have very remarkable effects.

The good thing is that androgenetic alopecia products are available in the market. A quick search on the internet will give you an immediate or lasting solution.

Female Pattern Baldness Treatments and Diagnosis

Clinical features of pattern baldness in women usually occur during early teens and late middle age. This is shown by the gradual thinning of hair over the frontal area. Usually, pattern baldness in women is not accompanied by increased shedding of hair, but unlike telogen effluvium, hair loss may be seen from the start. The scalp becomes more and more visible as the disease progresses.

Most of the time, the central part of the head widens due to diffused reduction of the hair’s density, which involves the frontal scalp and crown. Some women may experience hair loss on some small areas of the frontal scalp while others may experience the effect on the entire scalp including the areas of parietal and occipital. During hair loss, women usually retain a rim of hair along the frontal hairline.

Laboratory Evaluation

Most women with pattern baldness have normal menstruation, normal fertility, and normal endocrine function, including correct levels of circulating androgens. Therefore, they would only need extensive hormonal testing when symptoms and signs of androgen excess become really visible. Laboratory measurement of serum total or free testosterone, dehydroepiandrosterone sulfate and prolactin are appropriate when hirsutism, severe unresponsive cystic acne, virilization, or galactorrhoea are present. Measurement of serum thyrotropin, serum iron and ferritin, and complete blood count may eliminate common causes of hair loss.

Differential Diagnosis of Androgenetic Alopecia

Androgenetic alopecia in women (external link) can be confused with the former condition. This is in spite of the fact that features of chronic telogen effluvium are distinct. Anyway, horizontal sections of a scalp biopsy help to distinguish the two conditions once the ratio of terminal hairs shrinks.


As time goes by, the hairs in pattern baldness become progressively miniaturized. These hairs include the papillae and matrices, as well as the hair shafts. However, the degree of hair loss in women is not as extreme as it is with some men. Women with pattern hair loss have a mosaic of variable-diameter hairs in the affected region of the top of the scalp. Increased spacing between hairs makes the central part appear wider over the frontal scalp compared to the occipital scalp.

In some cases, hair volume may still appear normal but the hair would stop growing to its previous length and normally results to thin distal ends. Female pattern hair loss is seen on women by visual decrease in hair density while in men, it is by baldness on the affected areas.

Treatment of Androgenetic Alopecia

Hair loss is a result of abnormal hair cycle. Because of this, it is theoretically reversible. However, the current treatment options have limits in their performance and in some cases, only small improvements in hair density can be seen. Advanced pattern baldness may already be difficult to treat because irreparable damages may have already taken place on the follicular stem cell when inflammation surrounded the bulge area of the follicle. Some systematic treatment plans for this case include:

  • The current treatment for pattern baldness is Minoxidil. The exact mechanism by which Minoxidil works is not known but the treatment appears to affect the hair follicle in three ways: it increases the span of time follicles spend in anagen, it rouses follicles that are in catagen and it enlarges the actual follicles. In effect, vellus hairs enlarge and are converted to terminal hairs, and shedding is reduced.
  • Exogenous estrogen can be used to treat pattern baldness, but this regimen is no longer much in use because of Minoxidil’s efficacy.
  • Finasteride has been effective on men with pattern baldness but definitely it was risky on women. This regimen is not advisable for women who are still in their childbearing age because of the presence of 5a-reductase inhibitors that may cause external genitalia abnormalities in male fetuses.
  • Hairstyling, teasing, coloring, permanents, and the use of hair spray are means of coping with the cosmetic effects of pattern baldness. However, when the hair loss is grave, the affected person may opt to use wigs.
  • Hair transplantation is another option since it has already been accepted in treating pattern baldness on men. Now, it is also being used to treat female hair loss although only a very few women go for this type of treatment because of the cost and the possible trauma that may go with it.
  • For those women who have encountered ineffective and unsuccessful treatments for hair loss, surgery may be another option and thus, the most suited method for them.


Pattern hair loss in women is made up of many factors whose traits are genetically determined. It is possible that both androgen-dependent and androgen-independent mechanisms contribute to this strange form of hair loss. In women, it is usually patterned with the most marked thinning over the frontal and parietal scalp, and with greater density over the occipital scalp. Unusual hair loss in women may frustrate self-esteem, psychological well being, and body image. Because of this, it is quite vital for the physician to inform their affected patients that hair loss could bring about adverse effects on the quality of a person’s life.

Thinning Hair in Women

It has become commonly acceptable for men to suffer from baldness, but this does not stop them from feeling embarrassed. This is why most men look for ways to stop this condition. If it is this bad for men, imagine how a woman must feel to realize that she is losing hair. Once a woman’s hair begins to thin, she begins to lose confidence in herself as well.

Looking for causes.

If you are experiencing an extensive amount of hair fall, then ask yourself a few questions before you panic. See if your diet has been poor recently, or if you have been under a lot of pressure in your professional or personal life. Another reason may be a particular hairstyle in which you tie your hair back really tight. These things may look insignificant at first, but they play an important role in the health of your hair and scalp.

There is a possibility that none of these things apply to your situation, and if you are losing more hair than any of the reasons mentioned above would cause, then your problem could be related to your hormones. Changes in hormones have the ability to effect hair growth tremendously. Discussed here are a few common things that may happen to a woman to alter her hormones and hinder the growth of her hair.

Hormones role.

women_thinning_hair_2The first thing you should check is whether you are undergoing menopause. This has a major impact on your hormones, and it mainly slows the production of female hormones in your body. Menopause is a very common reason for thinning hair in women, and the most frequent treatment for the hormonal imbalance it causes is Hormone Replacement Therapy (HRT).

To explain the hormonal imbalance better and how it affects hair loss, you should know that before menopause, women produce both testosterone and estrogen, but this estrogen stops the testosterone to convert and go around the body. However, after menopause the estrogen levels in the body diminish and thus the testosterone is able to escape into the body. It then turns into DHT and if any area of the scalp is sensitive to this, hair will begin to thin out. Hysterectomy is also like menopause, and has the same effects on the scalp. Pregnancy is another cause for thinning hair in women, due to the massive hormonal changes that occur within her body.